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As NAC is considered a safe drug with low toxicity and mild side effects including nausea, vomiting, tachycardia, and pruritus, there is no fear to administrate it in high doses [55]

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Just avoid mixing with hot liquids, as heat can degrade the liposomal structure

Accordingly, a study was conducted by Upritchard et al

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The lactam bridge between Asp5 and Lys10 side chains cyclises the heptapeptide backbone and constraining it into a compact, conformationally rigid structure that stabilises the receptor-binding pharmacophore conformation required for high-affinity MC3R and MC4R engagement