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This toxic metabolite is immediately conjugated with glutathione to form mercapturic acid, which is then excreted in urine

In sponge exudates, it remains active at the site of wounds for several hours (Tkalcevic et al., 2007)

Moderate dose (3-4 mg daily): Applied for more noticeable skin repair or wound healing

The most common side effects are extremely mild and infrequent, primarily involving occasional skin irritation, mild redness, or transient tingling sensation in a small percentage of users, typically resolving without intervention and not requiring discontinuation

It's worth knowing that the strength of glutathione is diminished through cooking though

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov D, Brcic L, et al