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To ask how -KG insufficiency depletes the cytosolic NADPH pool, we first confirmed that cytosolic NADPH-producing enzymes ME1 and IDH1 are essential for cell survival during energy stress, as previously reported 26,31 , because knockdown of either gene sensitized Huh7 and H1299 cells to glucose starvation (Supplementary Fig
BPC-157, also known as Body Protection Compound 157, is a synthetic peptide consisting of 15 amino acids, making it a pentadecapeptide
This partially suppressed VEGFA and IL8 expression, suggesting that STAT6 contributes, at least in part, to ferroptosis-mediated VEGFA and IL8 production (Fig
Yang J, Jiang Z, Wang Y, Qureshi IA, Wu XD
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