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Begin reintroducing previously reactive foods one at a time, monitoring for reactions Weeks 9 to 12: Assess which food reactions have diminished

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Xanthurenic acid, the major downstream metabolite of 3-HK capable of crossing the BBB, exhibits both antioxidant and pro-oxidant properties depending on experimental context [158, 161,162,163]

Topical and microinfusion-delivered PDRN is the newer application, with literature growing rapidly since 2020

Clinically, peptides are grouped by role some act as endogenous messengers, others are formulated as therapeutic agents to target particular pathways

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