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Working with a healthcare provider to develop a discontinuation plan is still advisable, but withdrawal symptoms are typically minimal compared to benzodiazepines

In this context, we generated MRP1/MRP2 chimeras covering different regions, MRP2 being a close homolog that does not trigger CS

Some countries UAE, Japan, Singapore, South Korea have stricter import rules and may require advance approval or specific import certificates (Japan's Yakkan Shoumei, for example)

If sleep disruption is more problematic than nausea, stick with morning

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