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Share: People with obesity who lost weight while taking popular medications such as Ozempic, Wegovy, Mounjaro, and Zepbound became significantly less physically active, according to research presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Illinois

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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

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However, its use during pregnancy is not yet fully understood, which is why its critical to consult with a healthcare provider before considering tirzepatide if you are pregnant or planning to become pregnant