Overall, GLP-1 receptor agonists may be useful for selected patients with obesity-related KOA, but their use requires careful patient selection, dose titration, adverse-event monitoring, nutritional and functional support, perioperative coordination, and realistic planning for long-term adherence
PMID: 42260976 Nat Commun 2019 Jun 20;10(1):2701
17 Recent advances in pharmacological treatments Sodium-glucose cotransporter-2 inhibitors SGLT-2 inhibitors (empagliflozin and dapagliflozin) are recommended in most people with type 2 diabetes and CKD, given the strong evidence that SGLT-2 inhibitors reduce CKD progression, heart failure and the risk of atherosclerotic CV disease in people with type 2 diabetes and CKD
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The composition of claim 3 wherein the LOD 75 C is no more than 2 %
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