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Studies suggest that various molecular pathways are involved in IC/BPS, including the JUN N-terminal kinase (JNK) pathway, transient receptor potential (TRP) channels, activated mast cells, mucosal signalling, circadian rhythm regulation, inflammation and neural dysregulation

The honest framing for research is that Epithalon is an interesting tool for studying telomere biology and pineal-axis questions, not a demonstrated intervention in human aging

JAMA Internal Medicine, 180 (3), 458-459

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B12 is a complex vitamin, it does amazing work in the body, but it cant miraculously eek itself out over 3 months, it is excreted quickly as is the nature of all water soluble vitamins

The study established that oral glutathione raises blood GSH markers