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Tregs produce inhibitory cytokines, kill effector cells via granzymes and perforins, and compete with effector T cells to deplete IL-2 [100]

doi:10.1073/pnas.1400472111 Polack, F

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Another important mediator, Zip7, facilitates zinc transfer from the endoplasmic reticulum to the cytoplasm within RPE cells, a process responsive to inflammatory cytokines such as IL-1 and TNF-