dulaglutide In the first target trial emulation, researchers used propensity score matching to compare 9,233 adults prescribed tirzepatide with 9,233 adults prescribed dulaglutide
Bechlioulis A, Markozannes G, Chionidi I, et al
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[2] The most frequent symptoms include nausea, vomiting, diarrhoea, constipation, abdominal pain, and dyspepsia
However, subgroup analyses from the TOPCAT clinical trial indicated that patients enrolled from the Americas, where adherence to therapy was higher, experienced notably higher rates of hyperkalemia compared to those from Russia and Georgiasupporting the hypothesis that increased exposure to spironolactone may have contributed to the regional differences in adverse event profiles [56]