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Subsequently, bacteria and endotoxins are translocated into the liver through the portal vein, activating the TLR4/NF-B signaling pathway of liver Kupffer cells, and promoting the liver inflammatory cascade and fibrosis development (Jiang and Schnabl, 2020)

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In addition to mimicking GLP-1 and GIP, retatrutide also targets the glucagon receptor, a crucial hormone in glucose and lipid metabolism, further enhancing body weight loss

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Increase oxygen levels for the muscles