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GLP-1 (glucagon-like peptide-1) agonists, such as Ozempic and Wegovy, have been in the news because of their soaring popularity with celebrities for dramatic weight loss

Transcytosis An energy-requiring mode of transport across cells that involves vesicles endocytosing from one membrane (for example, blood side) and releasing contents at the opposite side (for example, brain side)

Psychiatric illness, adverse effects of prescription and over-the-counter medications, and substance use should also be considered

Further experiments revealed that the natural products periplocin, oleandrin and ginkgetin can be used as senolytic agents

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