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PMID 16527179

When prescribed for weight loss, this constitutes off-label use-a practice permitted under medical judgment but outside the FDA-approved indication

[18] [19] Patients should be counselled to report symptoms of liver injury (jaundice, dark urine, right upper quadrant pain) or infection immediately

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The Mechanisms of Semaglutide Therapy in Heart Failure Patients trial will assess the impact of semaglutide on biomarkers, echocardiographic parameters, and functional outcomes in patients with HF [63]