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To provide the right care for patients taking GLP-1s, physical therapists and care teams must be versed on the impact that obesity and diabetes have on the entire MSK system, particularly diminished tendon health, impaired muscle function and joint degradation
doi: 10.1186/s12944-023-01867-3 39
Of particular note are a randomised, placebo-controlled trial enrolling participants with impaired glucose tolerance [108], testing metformin up to 1 g twice daily versus placebo for 2 years, and a trial (MET-PREVENT) [109] enrolling older people with probable sarcopenia, testing metformin 500 mg three times a day versus placebo for 4 months
When to Talk to Your Doctor If you do notice significant changes in your menstrual cycle while using semaglutide and an IUD, it is a good idea to talk to your healthcare provider

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