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The mechanism that links lipogenesis with phagocytosis was later elucidated by Lee et al., who showed that phagocytosis was impaired in LPS-activated Ms isolated from mice deficient in sterol regulatory element binding protein 1a (SREBP-1a) (19), which regulates the transcription of genes related to lipogenesis (20)

Such correlation was lost when we considered only the intervention group ( r = 0.369, p = 0.84)

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Distribution and Protein Binding Evolocumab distributes largely in plasma and interstitial fluid, where it binds circulating PCSK9

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