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Upon activation, Nrf2 translocates to the nucleus, binds specifically to the Antioxidant Response Element (ARE) and induces transcription of downstream genes (Baird and Dinkova-Kostova, 2011) (Figure 2B)
PMID 11710935
Supplemental glutathione can support healthy cell function , but its absorption is greatly inhibited by breakdown in the stomach
References Benard, G
Because cysteine can cross the blood-brain barrier, this supplement offered promise for some as a way to boost GSH levels in neuronal dysfunction such as Parkinsons
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