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Novo Nordisk spent a billion dollars on marketing in 2021-2022 and took 239,000 doctors to dinner and lunch, essentially educating the entire market on a critical concept: weight management is a physiological, hormonally-driven process, not about willpower

Around two-thirds of drugs that met the 1938 safety requirement failed the 1962 efficacy bar

Int J Mol Sci 25(2):1213 Letukien A, Hendrixson V, Gineviien V (2024) Current knowledge and scientific trends in myokines and exercise research in the context of obesity

Use an insulin syringe to draw the calculated dose from the vial, select an injection site (abdomen or thigh are most common), pinch the skin, insert the needle at a 45-90 degree angle, and inject slowly

Initially, you can have it on alternate nights