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Experimental data suggest that peptides influencing melatonin expression, including MT-1, may reduce T-cell activity in models of multiple sclerosis and uveitis

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The thymus shrinks due to the pressure of hormones such as androgens, estrogens, progesterones, and corticosteroids, with the majority of the shrinkage occurring in the 20s and 30s, a process known as thymic involution, 2m6s