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Activation of caspase-4 subsequently activates GSDMD, and the Damage-Associated Molecular Pattern (DAMPs) released can activate the inflammasome (Kayagaki et al., 2015

Metformin also works well as a foundation medication when combined with GLP-1 therapy

The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transpoter

Acta 1005 , 1319 (1989)

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