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Lower GPX3 levels in the plasma and tumor tissue of non-small-cell lung cancer, glioblastoma, hepatocellular carcinoma and colorectal carcinoma have been linked to selenium deficiency and increased lipid peroxidation, supporting the notion that loss of GPX3 contributes to oxidative stress [120]

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The trial did have a conflict of interest in that it received support from a company that provides Setria, but it was also a randomized, double-blinded, and placebo-controlled trial with sound methods

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