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In addition, metformin activated p-AMPK and promoted the translocation of Pink1 from the cytoplasm to mitochondria, thereby promoting the occurrence of mitophagy in HK-2 cells under HG/HFA ambience (141)

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Secondly, the purified GST-STAT3-CCD (218-400), GST-STAT3-DBD (401-564), GST-STAT3-linker (565-663), and GST-STAT3-SH2 (664-768) fragments were bound to glutathione resin as a GST-fusion protein and incubated with anti-GSTP1 for 2 h at 4C