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GLP-1-based therapies led to favorable changes in body composition, with significant reductions in VAT and FBM, particularly during the first six months
Understanding these differences can inform decisions about which medication might be most appropriate for individuals interested in potential alcohol-related benefits
The dosing schedule follows a gradual ramp-up to help minimize side effects and improve tolerance
People who have side effects like nausea when they begin to increase their dose typically stay at the largest dose they can tolerate instead of escalating until hitting the maximum dose as the FDA recommends
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Only 11.2% of participants stopped the trial due to side effects, and the discontinuation rate dropped significantly after week 24, suggesting those who make it through the early phase generally tolerate it well long-term
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