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doi: 10.1016/S0140-6736(14)61375-1 26 PivonelloRDe MartinoMCDe LeoMLombardiGColaoA

McKlveen, S

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The effects of flavonoids in cardiovascular diseases

This involvement in nucleotide synthesis contributes to the maintenance of genetic material in nerve cells (6).Additionally, PLP plays a role in homocysteine metabolism, catalyzing the reaction that forms 5,10-methylene-THF, needed for the methylation of homocysteine to methionine,which also depends upon B2, B6, B9 and B12 vitamins (6, 11, 57, 58) ( Figure 5 )