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Description

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The importance of GPR119 in the fat-induced incretin secretion is demonstrated by the impaired incretin signaling displayed by transgenic animals deficient for this protein only in PG expressing intestinal cells

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RETA treatment dramatically delayed LLC tumor onset, with unpalpable tumors in the RETA treated group until day 16, compared to onset observed in Veh treated mice where tumors were palpated starting on day 10 (Fig

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Furthermore, such a retrospective design inherently limits the identification of causal relationships, and unmeasured residual confounding variablessuch as glycemic control, hypoglycemic episodes, familial suicide history, and socioeconomic statusmay persist

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