While Novo Nordisk has not yet reached an agreement, pressure to comply is mounting
Arthritis is not a single condition
Newer diabetes medications like GLP-1 receptor agonists (Ozempic, Mounjaro) seem to promote the most weight loss, while oral drugs like metformin and SGLT2 Inhibitors (Jardiance) tend to lead to more modest outcomes for weight
GLP-1 inhibits FoxO1, promoting -cell proliferation, and enhances PDX1 activity, thereby stimulating cellular proliferation
KM is funded by BBSRC project grant BB/I001816/1
10,11 Improved Glycaemic Control In addition to their direct effects on the pancreas, GLP-1RAs improve insulin sensitivity in peripheral tissues, like skeletal muscle and the liver