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Participants were randomized 1:1 to once-weekly subcutaneous semaglutide (dose escalation from 0.25 mg to 0.5 mg to 1.0 mg, then maintained at 1.0 mg through week 32) or matching placebo

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The implications of commonalities and differences in insulin and GLP-1 secretions would provide deep insights into the coordination between blood glucose levels and the maintenance of body homeostasis

Here, using a mouse model of lipopolysaccharide-induced neuroinflammation, we investigated how semaglutide coordinates cellular responses to resolve neuroinflammation

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