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In addition, they are also the main source of ROS based on electron leakage from the respiratory chain (Scial et al., 2017)

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Because correlation is not causation

The rapid evolution of obesity therapeutics coincides with a broader global health crisis

FEBS J 283:22192232 Sancho P, Mainez J, Crosas-Molist E, Roncero C, Fernandez-Rodriguez CM, Pinedo F, Huber H, Eferl R, Mikulits W, Fabregat I (2012) NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development