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Using a double immunofluorescence procedure with antibodies against specific membrane antigens of red blood cells (glycophorin A) and platelets (CD41a), the authors demonstrated that nearly 50% of the microparticles were derived from erythrocytes, 30% from platelets, and the remainder from poorly identified cells [144]
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Disruptions in redox balance can have detrimental health effects [78]
Mutations in the KCNJ11 gene are associated with MODY13, transient neonatal diabetes mellitus type 3 (TNDM3), permanent neonatal diabetes mellitus (PNDM), familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), and also contributes to an autosomal dominant form of type 2 diabetes
