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Interestingly, RJ pretreatment markedly reduced the expression of Bax and caspase-3, and markedly increased Bcl-2 expression compared with the Cd-treated group (Table 1)

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Dosing with ICIs may be continued with low grade GI irAEs, however close monitoring for dehydration and adjustments to diet and nutritional requirements is warranted

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[DOI] [PubMed] [Google Scholar] Calabrese V, Scapagnini G, Catalano C, Dinotta F, Bates TE, Calvani M, Stella AMG (2001) Effects of acetylLcarnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after shortterm ethanol administration in rat