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At the same time, this review discusses the potential therapeutic strategies targeting amino acid metabolism and their translational challenges

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To understand if the lower lactate concentrations during exercise after GRS is due to an increase in mitochondrial content, we assessed the activity of citrate synthase in the muscle tissue, but found it was unchanged in both conditions (from 6.5 2.4 to 6.9 4.6 in PLA and 6.6 2.3 to 6.9 3.0 mol min1 g1 dw in GRS)

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