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Neurohormonal changes in the Gut-Brain Axis and underlying neuroendocrine mechanisms following bariatric surgery

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Dysfunction of the sphincter of Oddi, located at the opening of the common bile duct into the small intestine, is a cause in some cases of post-cholecystectomy syndrome, but more frequently the cause is an overlooked disorder outside of the biliary system, such as peptic ulcer, chronic pancreatitis, or irritable bowel syndrome, or is unknown (Tarnasky 2016

Hampel H, Hardy J, Blennow K et al (2021) The amyloid- pathway in Alzheimers disease

This decrease in muscle mass can put more strain on tendons and adjacent bones and potentially lead to a higher risk of injury, though at present this is just hypothetical