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In the thyroid tissue of the GD group, miR-146a1 was significantly decreased in comparison to the control group (mean relative expression 5.17 vs

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The slower release of LS from F1 compared to free LS solution would be credited to the high transition temperate of Span 60 that offers a more rigid and less permeable vesicle structure, leading to a delayed rate of drug release 57

Journal Clinical Pharmacology 56 (6), 635638