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Neural Regeneration Research, 2022, 17 3

However, patients with type 2 diabetes were included in these trials [52, 53], which could have contributed to the observed differences

Sowden HM, Naseem KM, Tobin DJ

The increased levels of choline in COC users may be the result of increased synthesis via phosphatidylethanolamine N-methyltransferase (PEMT), since estrogen treatment has been found to increase the activity of PEMT, leading to increased synthesis of choline 42

There is meaningful interest in GHK-Cu for skin regeneration and remodeling, but patients should know the evidence is still not the same as having large, acne-scar-specific human trials proving strong visible improvement in post-Accutane scarring