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167 Lactobacillus L15 and Lactobacillus C4 can also protect the integrity of the intestinal barrier by decreasing the expression levels of proinflammatory cytokines and upregulating the expression of tight junction proteins and mucin-2 (MUC2)

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In the case of lactate further analysis revealed that this was driven by the difference between patients with ME/CFS and HC (F = 8.618, p = 0.006), with ME/CFS patients showing higher lactate levels than controls, similar to pgACC

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