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A novel 11beta-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits
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For researchers studying wound biology, the combined peptide system provides a model for exploring how vascular signaling pathways and cytoskeletal-regulated cell movement interact during tissue remodeling processes
In parallel, the effect of the drugs were simulated using an adapted version of the singleGeneDeletion of the COBRA toolbox [28] (Drug Deletion function): Therefore, DrugBank v5.1.3 [29] was mined to identify 1175 drugs inhibiting metabolic genes (genes present in Recon 2.04) and their targets that were then used as input for the Drug Deletion function
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Comparative effects of GLP-1 and GLP-2 on beta-cell function, glucose homeostasis and appetite regulation
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