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Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility

Targeting of nanoparticles to different cell types in the glomerulus or to the glomerular basement membrane can be achieved through fine-tuning of their physicochemical properties based on our understanding of glomerular filtration and the glomerular filtration barrier

Broad-spectrum antibiotics are administered to control bacterial infection and therapy for esophagitis should be instituted as described previously