doi: 10.1016/j.cmet.2009.02.002 38 WangTJLarsonMGVasanRSChengSRheeEPMcCabeEet al
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Notably, while total FOXO4 protein levels remained consistent between young and elderly men, a striking age-dependent shift in its subcellular localization was observed: FOXO4 predominantly resided in the cytoplasm in young Leydig cells but translocated to the nucleus in aged cells
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Most are mild, often linked to how the medication affects your stomach and appetite, and improve over time, particularly after the early weeks of treatment or dose increases
Discussion PCCA or PCCB mutations result in impaired propionyl-CoA catabolism and various complications in patients with PA
