microdosing glp-1 research One Size Does Not Fit All: Understanding Semaglutide for Diabetes in Multidose Pens What is GLP-1 Microdosing? |

For semaglutide specifically, a 2025 preformulation study tested stability at 5C, 25C, 40C, 60C, and 80C and documented accelerated degradation at higher temperatures, supporting the practice of minimizing heat exposure and refrigerating whenever possible

10.1038/302716a0 9 BornerT.ShaulsonE

These rigorous phase 3 studies enrolled over 10,000 participants and demonstrated both efficacy and an acceptable safety profile consistent with the incretin-based medication class

You cannot take a higher dosage 12mg/weekly

He is a Director at Large of the Canadian Nutrition Society (CNS), a founding member of the International Carbohydrate Quality Consortium (ICQC), an Executive Board Member of the Diabetes and Nutrition Study Group (DNSG) of the EASD, and a director of the Toronto 3D Knowledge Synthesis and Clinical Trials foundation

Zepbound is now FDA-approved for OSA