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One in vitro study appears to suggest the half-life of DSIP to be around 15 minutes, while animal studies suggest 4-5 minutes

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However, no significant change in p-JNK protein level was observed in HUVECs (Figure 6)

Humana Press, Totowa Greenberg ME, Li XM, Gugiu BG, Gu X, Qin J, Salomon RG, Hazen SL (2008) The lipid Whisker model of the structure of oxidized cell membranes

All tested compounds were found to cause eryptosis by externalizing PS and activating caspase-3

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