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Before considering digestive enzyme supplementation , patients should undergo appropriate clinical assessment

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In a similar rat model, Mazo et al., 2013 [17] showed that the administration of SNAC at 1.4 mg/kg daily by gavage for 8 weeks could reduce the collagen-occupied area associated with an upregulation of matrix metalloproteinases-13 and -9 and a downregulation of heat-shock protein-60, tissue inhibitors of metalloproteinase-2, TGF-1, and collagen-1

Acknowledgment The authors gratefully acknowledge the Scientific Publishing Department, Health Research Center, Ministry of Defense Health Services, Riyadh, Saudi Arabia, for the English language editing

Slowed gastric emptying caused by GLP-1 receptor activation means high-fat, fried, and ultra-processed foods are more likely to worsen nausea, bloating, and upper abdominal discomfort