For instance, phosphorylated forms of thiamin, including thiamin diphosphate (TDP) and thiamin pyrophosphate (TPP), are required cofactors for enzymes of glycolysis, the citric acid cycle, and the pentose phosphate pathway (22)
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The phospholipase A2 group VI (iPLA2) can reduce p53-mediated ferroptosis by removing oxidized PUFA tails from PLs (24) ( Figure 1 ), suggesting that oxidized PUFA must be present in a membrane-bound PL in order to trigger ferroptosis
Dickson, S
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