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This multifaceted action has made GLP-1 receptor agonistsmedications that mimic the effects of endogenous GLP-1valuable therapeutic agents for managing type 2 diabetes and, more recently, obesity

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Start at the lower right, move up to the ribs, across the top, and down the left side

Activation of the peripheral nervous system likely occurs primarily through stimulation of the hepatic vagal nerve in the portal area