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This is significantly lower than sublingual administration, which bypasses first-pass metabolism and delivers 6085% of the dose intact

10.1038/mt.2009.146

Rats were injected with 4% papain into the left knee joint to replicate a rat model of knee osteoarthritis

We have better news regarding the three magic abilities of vitamin C: there is in-vivo (tested on real people) data showing that SAP does have photo-protective (aka antioxidant) properties , though less than pure AA

Peripheral neuropathy affects millions of people and is a growing concern, particularly amongst individuals living with diabetes and those who have long term nutritional absorption issues