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Prog Brain Res

532 Upon receiving certain cues, cancer stem cells can differentiate to give rise to the cancer cells or cancer cells can de-differentiate back to their CSC state

Additionally, paeoniflorin was reported to reduce the expression of the L-tryptophan-catabolizing enzyme tryptophan-2,3-dioxygenase in the liver of stress-induced depressive mice, thereby increasing the 5-hydroxytryptamine/tryptophan ratio and decreasing the kynurenine/tryptophan ratio (Liang et al., 2023)

This choice depends on the patients health and the doctors advice

10.1016/j.chemosphere.2008.09.082 Chemosphere 3 ChanC.LamH

NMDA and AMPA receptors mediate intracellular calcium increase in rat cortical astrocytes