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[DOI] [PubMed] [Google Scholar] 281.van Pel M

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In conclusion, the structure of the GLP-2GLP-2RG s complex delineates detailed interactions between GLP-2 and GLP-2R that account for the peptide binding specificity, and provides new insights into the structural reorganization of class B GPCRs upon activation

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The transduction ratio (tau/Ka) was extracted from standard concentration-response data that was analysed with the operational model of agonism (Kenakin & Christopoulos 2012)

In this model, GHR is globally ablated and an IGF-I transgene is expressed in liver to restore serum IGF-I levels