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The five inhibitors considered in the present investigation are thiamine (vitamin B1 ), pantothenic acid (vitamin B5 ), pyridoxine (vitamin B6 ), Biotin (vitamin B7 ), -tocopherol (vitamin E ), and glutathione ( GSH ), their 2D structures are shown in Fig
Hydrogen peroxide causes a change in Cys121 of MAT by generating hydroxyl radicals, leading to the inactivation of MAT and a decrease in SAM biosynthesis
When oxidative stress is rampant in the body, disease states may occur over time
8c, f, Supplementary Figs
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