results of retatrutide TRANSCEND-T2D-1 topline are out : r/Zepbound Best Retatrutide Peptide (Triple Agonist)

However, there are on the horizon no cardiorenal outcome studies comparing SGLT-2 inhibitors with GLP-1RA, so it is likely that we must rely on indirect comparisons

Phase III, PIONEER Program Multiple phase III efficacy trials have been fully published and/or presented in abstract form

If everything goes well, approval could happen as soon as 2026

While both compounds produce gastrointestinal side effects common to all incretin-based therapies, their severity and impact on treatment continuation differ markedly

This response is metabolic, not pharmaceutical

Always double-check whether you are working in mg or mcg values