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Importantly, 70-80% of participants achieved at least 10% weight loss (the threshold for clinically meaningful benefits), and 50-60% achieved at least 20% weight loss (approaching surgical weight loss results without surgery)

This is often when side effects are most prominent

The effect of GLP-1 agonists on risk of gastric cancer appears very uncertain

ACEi=angiotensin-converting enzyme inhibitor

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Cramp severity was assessed and recorded based on the Visual Analog Scale (VAS) [13]