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The estimated cost of obesity in the region was more than 3bn in the cost of NHS treatment, social care and quality of life, according to a 2023 report by consultants Health Innovation Manchester

Table 4 Recommendations for policymakers and healthcare systems

Long-term Outcomes Semaglutide and Tirzepatide are part of a comprehensive approach to weight loss

As a GLP-1 receptor agonist, semaglutide's primary role in diabetes management is its powerful ability to regulate blood glucose

This dose escalation schedule is designed to improve tolerability while achieving therapeutic blood levels necessary for optimal glycemic control and weight reduction

Exercise programming Resistance training is non-negotiable during semaglutide use