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2001, AOD-9604 lost most of this fat-metabolism effect in mice that were genetically missing the beta-3 adrenergic receptor, suggesting that pathway carries part of the signal

doi: 10.3389/fnut.2025.1661136 Received 07 July 2025 Accepted 10 October 2025 Published 27 October 2025 Volume 12 - 2025 Edited by Xuchang Zhou, The First Affiliated Hospital of Xiamen University, China Reviewed by Uzma Amin, Chongqing Medical University, China Syed Nasar Rahaman, Central Leather Research Institute (CSIR), India Updates Copyright 2025 Wang, Cao, Gao, Shao, Gao, Dong, Tian, Feng, Xu and Xiang

[DOI] [PubMed] [Google Scholar] 15.Kandalla P.K., Goldspink G., Butler-Browne G., Mouly V

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excess B12 is excreted in urine, and the UK has not established an upper safe limit